99% Lidocaine base, Cas 137-58-6 local anesthetic manufacturer

Description

What's lidocaine?

Firstly, Lidocaine is a local anesthetic and antiarrhythmic drug. Used for infiltration anesthesia, epidural anesthesia, surface anesthesia (including in the thoracoscopy or abdominal surgery for mucosal anesthesia) and nerve conduction block.

Secondly,Lidocaine is an amide local anesthetic.
With the dose increased, the role or toxicity increased, there is an anti-convulsive effect with sub-poisoning plasma concentration;
Blood concentration of more than 5μg ? ml-1 can occur convulsions.

Third,Lidocaine in low doses can promote outflow of K+ in cardiomyocytes, reduce myocardial autonomy, and has antiarrhythmic effects.

Usage of Lidocaine:

1.Topical lidocaine has been shown in some patients to relieve the pain of postherpetic neuralgia (a complication of shingles), though there is not enough study evidence to recommend it as a first-line treatment.

2.Lidocaine also has uses as a temporary fix for tinnitus. Although not completely curing the disorder, it has been shown to reduce the effects by around two thirds.

3.Lidocaine hydrochloride injection administered intravenously or intramuscularly, is specifically indicated in the acute management of ventricular arrhythmias such as those occurring in relation to acute myocardial infarction, or during cardiac manipulation, such as cardiac surgery.

Product Name

Lidocaine Base

Other Name

2-(Diethylamino)-N-(2,6-dimethylphenyl) acetamide

Assay (%)

≥99.5

Odor

Characteristic

Color

White crystalline powder

Cas No.

137-58-6

Molecular Formula

C₁₄H₂₂N₂O

Molecular Weight

270.7982

Standard

BP/USP/EP

Function

Main functions are as follows:
1. Local anesthetic.
2. Treating Epilepsy.
3. Treating Asthma.

Applications

Main applications are as follows:
Applied in pharmaceutical fields.

Packing

1kg or 5kg/bag, 25kg/drum

Shelf Life

24 months

Storage

Store in sealed containers at cool & dry place. Protect from light, moisture and pest infestation.

ITEMS	SPECIFICATIONS	RESULTS
Appearance	White crystalline powder	Pass
Content Wt.	99.00%-101.00%	99.52%
Identification	Chloridate	Positive
Identification	Test A	Positive
Melting point	74-79 degree	76-78 degree
Appearance of solution	Clear and colourless	Pass
Water	5.5-7.0%	6.7%
Acidity PH	4.0-5.5	5.2
Sulphated ash	0.10% max	0.08%
Heavy metals	5ppm max	Pass
2, 6-Dimethylaniline	100ppm max	Pass

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