99% Apigenin Powder Cas 520-36-5 a natural flavonoid, antioxidant

What Is Apigenin?

Apigenin is a flavonoid that’s widely distributed in the plant kingdom. It acts as a free-radical scavenger and antioxidant that diminishes oxidative stress.

It’s a glycoside, which is a term referring to molecules that are connected to sugar molecules.

Flavonoids are a class of naturally occurring phytochemicals in plant tissues. They play a protective role in plants against pathogens and sunlight radiation. They also help attract pollinators and regulate plant metabolism.

Apigenin Benefits

Apigenin is known to offer a range of health benefits, from supporting heart and brain health to promoting healthier skin. Most of the studies involving the flavonoid use animal models, but they highlight the potential mechanisms and benefits of this plant nutrient.

1. Works as an Antioxidant

Flavonoids are widely known for their antioxidant properties, and a number of studies show that apigenin, in particular, has significant antioxidant effects. It’s also an effective anti-inflammatory agent compared to other flavonoids.

Because of its antioxidant effects, the flavone is used to promote healthy aging and utilized to boost skin health. Topical apigenin is even used to fight acne and promote skin cell growth.

2. Has Antimicrobial Effects

Reports suggest that apigenin has “reverse antibiotic” activities against some bacteria, which means that it may be active against antibiotic-resistant bacteria and help reverse bacterial resistance. Researchers believe that the phytonutrient could be a candidate as a new antibiotic or as a dietary supplement to enhance the performance of antibiotics.

The nutrient also has proved to inhibit multiple viruses, including herpes; hepatitis C; influenza; hand, foot and mouth disease; and African swine fever.

3. Reduces Pain

Because of its anti-inflammatory effects, apigenin is able to reduce pain and discomfort related to inflammatory issues. This includes pain from digestive problems, infections, immune responses and migraine pain.
The flavonoid has been shown to decrease the release of cytokines, which can overproduce and lead to disease.

4. Supports Heart Health

Apigenin supports cardiovascular health by reducing blood pressure and inflammation. Animal models show that it has cardioprotective effects in rats with heart damage.

One animal study found that apigenin protected rats against heart attack by reducing edema, cell death and oxidative stress.

5. Boosts Brain Function

Apigenin has neuroprotective effects.

Research published in Neural Regeneration Research found that apigenin has cognition-enhancing effects because of its antioxidant and anti-inflammatory properties. In mice with Alzheimer’s disease, it was able to improve memory and learning deficits, and in humans it suppressed inflammatory mediators.

6. Eases Anxiety and Depression

This flavone is known for its relaxing and sedative effects. It has been shown to reduce cortisol levels, helping prevent the body’s response to chronic stress.

This explains why chamomile tea can have beneficial effects on anxiety and help aid relaxation and sleep.

Apigenin also has been shown to improve depression in rodents. Treatment with the flavone was able to elevate immobility time in mice that were induced by chronic corticosterone treatment.

7. Fights Diabetes

Animal studies suggest that apigenin improves insulin resistance and can be helpful for people with diabetes. One report found that the flavone improved impaired glucose tolerance and significantly decreased insulin resistance.

8. Works as an Anticancer Agent

Several experimental and biological studies suggest that apigenin works as an anticancer agent. A report published in Phytotherapy Research found that the flavonoid exhibits cell growth arrest and apoptosis in many types of tumors, including lung, liver, colon, prostate, pancreatic, breast, skin, blood and cervical.

Anticancer research further explores how apigenin plays a role in several cancer signaling pathways and should generate interest as a possible chemotherapeutic modality due to its low toxicity and effects on normal versus cancerous cells.

9. May Increase Testosterone

Lab studies suggest that apigenin plays a role in testosterone synthesis and blocks signaling of testosterone repressing proteins.

Because of its potential impact on hormone levels, it has become more popular to use apigenin for bodybuilding efforts. In this case, apigenin supplements are used to increase testosterone and potentially block estrogen production.

This may help with muscle growth, strength and energy levels.

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